Development, Strategies, and Challenges for Tularemia Vaccine

S Moradkasani, M Maurin, AS Farrokhi, S Esmaeili - Current Microbiology, 2024 - Springer
… such as Salmonella, Brucella, Legionella, and Yersinia spp. has … -12 conferred complete
protection against LVS challenge. This … as vaccines against tularemia in various animal models (…

[HTML][HTML] Biodefense and special pathogen vaccines

PR Pittman, SA Plotkin - Plotkin's Vaccines, 2018 - ncbi.nlm.nih.gov
… as a single dose, conferred protection against challenge with … to be related to Legionella
bacteria. Fever and pneumonia are … tularensis LVS were protected against a lethal respiratory …

[HTML][HTML] ClpB mutants of Francisella tularensis subspecies holarctica and tularensis are defective for type VI secretion and intracellular replication

A Alam, I Golovliov, E Javed, A Sjöstedt - Scientific Reports, 2018 - nature.com
… latter subspecies may cause fatal human infection, whereas … ClpB confers thermotolerance
to a range of species via its … and confers very effective protection in the mouse against

Listeria-Vectored Multiantigenic Tuberculosis Vaccine Enhances Protective Immunity against Aerosol Challenge with Virulent Mycobacterium tuberculosis in BCG …

Q Jia, S Masleša-Galić, S Nava, MA Horwitz - Mbio, 2022 - Am Soc Microbiol
vaccine is needed to boost the level of immunity conferred by … booster vaccines administered
to BCG-immunized animals (… role in vaccines against such pathogens, including Legionella

[HTML][HTML] Vaccination against bacterial infections: challenges, progress, and new approaches with a focus on intracellular bacteria

A Osterloh - Vaccines, 2022 - mdpi.com
tularensis develop to late endosomes that become acidic … Furthermore, the immunization
conferred protection against lethal … production and protected the animals from lethal challenge …

Galleria mellonella–intracellular bacteria pathogen infection models: the ins and outs

M Asai, Y Li, SM Newton, BD Robertson… - FEMS Microbiology …, 2023 - academic.oup.com
… FDA no longer requires animal testing for licensure. Further … and their ability to prevent lethal
infection is determined. Different … tularensis subspecies are facultative intracellular bacteria, …

AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity

SM Man, R Karki, TD Kanneganti - European journal of …, 2016 - Wiley Online Library
bacteria Francisella tularensis Live Vaccine Strain (LVS), F. … to prevent rupture of the
Legionella-containing vacuole and thereby … to confer inflammasome activation against A. …

[图书][B] Investigating the Roles of Francisella Encoded Factors and NLRP3 in Immunopathogenesis of Tularemia

RV Suresh - 2018 - search.proquest.com
… bacterium that causes the fatal disease known as tularemia. … tularensis capsule to confer
protection against serum … 57,61 In summary, there are a number of species and media …

Bacterial sphingomyelinases and phospholipases as virulence factors

M Flores-Díaz, L Monturiol-Gross… - Microbiology and …, 2016 - Am Soc Microbiol
… its permeability barrier and confer fitness for survival in certain … in the genomes of other
Legionella species, Pseudomonas … tularensis causes tularemia, a systemic disease with multiple …

The Role of MFS Family Transporters in the Lifecycle of Type A Francisella tularensis and Their Viability as Vaccine Targets

PMJ Balzano - 2018 - search.proquest.com
… ingestion, inhalation, and handling infected animals. That a small … are Coxiella burnetii and
Legionella pneumophila [216]. Two … tularensis LVS was found to confer full protection against